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Gray-Out — Targeted Topical Support for Equine Melanoma
Equine melanoma is an all-too-common challenge for gray horses, especially as they age. Around 80% of gray horses over 15 years old develop some form of melanoma — typically slow-growing, but stubborn and difficult to manage. Traditional options are limited: surgery isn’t always practical, and systemic treatments often fall short. That’s why many owners turn to topical support as part of a broader care plan — to help slow growth, protect skin health, and maintain comfort.
Gray-Out is an advanced, veterinarian-formulated topical designed to help manage equine melanoma externally with powerful plant extracts, antioxidants, and skin-repairing compounds. Each ingredient was selected for its research-backed ability to support healthy skin cell function, normal inflammation response, and overall skin integrity.
How Gray-Out Fights Melanoma Naturally
✅ Targets Abnormal Cell Proliferation
Frankincense has been researched for its boswellic acids, which help block pathways that allow tumor cells to spread unchecked. It’s one of the oldest natural supports for unwanted growths.
Turmeric (curcumin) is among the most studied natural compounds for its anti-tumor, anti-inflammatory, and antioxidant activity. Research suggests it can help modulate abnormal cell signaling and reduce factors that feed tumor growth.
Bakuchiol, a plant-based alternative to retinol, is increasingly researched for its ability to encourage healthy cell turnover while providing antioxidant and anti-proliferative support — helping the skin maintain normal regeneration cycles.
✅ Neutralizes Free Radicals that Drive Tumor Growth
Green Tea Extract delivers EGCG and other catechins that directly target oxidative stress, which can contribute to DNA damage and uncontrolled cell division.
Grapeseed Oil adds additional polyphenols and resveratrol-like compounds to combat free radicals right at the skin’s surface.
✅ Supports Skin Barrier Strength & Pigment Balance
Nicotinamide (Vitamin B3) has been studied for its role in DNA repair and healthy skin cell life cycles. It helps maintain proper pigmentation and supports normal, controlled cell division.
Tranexamic Acid (TXA) helps manage abnormal pigmentation and reduces inflammation that can damage surrounding tissue.
Hyaluronic Acid and Centella Asiatica deeply hydrate, soothe irritation, and help maintain collagen structure — giving the skin resilience to handle tumor stress and support recovery from minor ulcerations.
Equine melanoma may grow slowly, but it’s still cancer — its stubborn, often resistant to conventional treatments, and difficult to remove completely due to its typical locations around the tail, perineum, and sheath. Even chemotherapy offers limited results for many horses.
Gray-Out is designed as a gentle, research-backed tool to help manage melanoma externally — not by burning tumors off or causing open wounds, but by supporting the body’s natural ability to slow growth and hopefully reduce tumor size over time. Consistency and patience are key: daily use helps modify tumor behavior gradually while minimizing irritation, keeping your horse comfortable and their skin resilient.
Typical results seen in 90 days of consistent daily application. However, this product is designed for long-term use and managment.
**Best when combined with Lifespan oral supplement. Available as a bundle**
Gray-Out | Melanoma Cream
Apply a small amount to all affected areas daily.
If the irritation occurs or if the horse becomes pruritic (itchy), the application can be every other day or every two days.
It is common that the skin becomes lighter, loses pigment, with use.

